Professor, Department of of Biological Sciences & Bioengineering (BSBE)
Research Interest
Biomaterials, Tissue engineering, Regenerative medicine, Stem cell research, Bioprocess engineering and Environmental biotechnology. Our research focuses in developing cryogel biomaterials and smart polymers for application in cartilage, bone, skin and neural tissue engineering and drug delivery. Further we focus in applying the concept of cryogel bioreactor system for therapeutic protein production and for extracorporeal bioartificial lever support system. We focus in affinity based monolithic cryogel systems for type specific cell separation and stem cell separation. Incorporating smart polymeric materials, we try to establish intelligent drug delivery systems and develop animal models for rheumatoid arthritis. The cryogel matrices have also shown promise as filters for water and air purification.
Mishra R, Goel S.K, Gupta KC. and Kumar A. (2014). Biocomposite cryogels as tissue engineered biomaterials for regeneration of critical-sized cranial bone defects. Tissue Engineering A doi:10.1089/ten.tea.2013.0072.
Jain E. and Kumar A. (2013). Disposable polymeric cryogel bioreactor for therapeutic protein production. Nature Protocols 8 (5); 821-835.
Reddy RM, Srivastava A. and Kumar A. (2013). Monosaccharide-Responsive Phenyl-boronate- Polyol Cell Scaffolds for Cell Sheet and Tissue Engineering Applications. PLoS ONE Oct 22;8(10):e77861.
Bhat S, Tripathi A. and Kumar A. (2011). Supermacroprous chitosan-agarose-gelatin cryogels: In vitro characterization and in vivo assessment for cartilage tissue engineering. J Royal Society Interface 8(57), 540-554.
Kumar A. and Srivastava, A. (2010). Cell separation using cryogel based affinity chromatography. Nature protocols 5 (11), 1737-1747 (cover page article)
