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Switchable Tandem CAR-T Cells Targeting tMUC1 and ROR1 for Breast Cancer Immunotherapy
Switchable Tandem CAR-T Cells Targeting tMUC1 and ROR1 for Breast Cancer Immunotherapy (Prof. Sivaprakash, Biological sciences and Bioengineering)
The project aims to develop a proof of concept on the generation of bi-specific CAR-T cells combined with knockout of PD-1 immune checkpoint protein to overcome immune suppression of T cells in the tumor microenvironment and promote TNBC tumor killing. In addition, we will incorporate the safety switch (suicide gene) RQR8 into our CAR molecule, which will allow for the selective removal of administered CAR-T cells in the event of toxicity.
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Hfo2-Based Ferroelectrics for Low Power Memory…
Hfo2-Based Ferroelectrics for Low Power Memory Application (Prof. Shikhar Mishra, Materials Science and Engineering)This study aims to investigate the...
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Multispectral Stealth Solutions Covering Visible…
Multispectral Stealth Solutions Covering Visible, Nir, Thermal and Microwave Ranges Using Coating and Patterned Surfaces (Prof. R Vijaya, Physics)The ...
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Flexible Solid-Electrolyte Alternative chemistry…
Flexible Solid-Electrolyte Alternative chemistry Batteries (Flex SEA Bat) (Prof. Sudarshan Narayanan, Sustainable Energy Engineering)This project, sup...
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Development and characterization of regulatory…
Development and characterization of regulatory biomolecular circuits for plasmid copy numbers in synthetic biology (Prof. Abhilash Patel, Electrical E...
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Cyclic Thermal Testing of TBC Coated Superalloys…
Cyclic Thermal Testing of TBC Coated Superalloys in a Burner Rig (Prof. Abhijit Kushari, Aerospace Engineering)This project experimentally simulates G...
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Processing of TFT Array and Liquid Crystal Layer…
Processing of TFT Array and Liquid Crystal Layer and Their Integration with Metasufrace Antenna (Ashutosh Kumar Tripathi, FlexiE Centre)Space Applicat...
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Methods of Artificial Intelligence and Magneto-…
Methods of Artificial Intelligence and Magneto-electric Effects in the Dynamics and Motion Control Problems of Telecommunication Spacecraft (Prof. Dip...
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Bharat-GPT A Suite of Generative AI Tech for India
Bharat-GPT A Suite of Generative AI Tech for India (Prof. Arnab Bhattacharya, Computer Science & Engineering)The role of IIT Kanpur is to lead the...
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Information Security Education and Awareness (…
Information Security Education and Awareness (ISEA) Project Phase-III (Prof. Urbi Chatterjee, Computer Science & Engineering)The research aims to ...
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Design and Development of Quantum Entanglement-…
Design and Development of Quantum Entanglement-enhanced Imaging Systems (Prof. Anand Kumar Jha, Physics)The project is on developing quantum-entanglem...
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