Slide background

The CoE for infectious diseases focuses on technological advancement and the development of diagnostics, therapeutics, and preventive measures. The centre is establishing methods and preventive tools to restrain the spread of infectious diseases, early and accurate diagnosis, and prognosis of infectious diseases. Ongoing research is developing appropriate therapeutics to cure infectious diseases.

Technology Demonstrator Project

Technology Platform for Rapid and Total Eradication of Topical Gram-negative Bacteria via Plasmonic Heating

The project is developing a technology to eradicate gram-negative bacterial cells selectively and efficiently, without affecting host cells. The first step is a non-lethal approach, where bacterial cells will be kept intentionally alive so that the host cells stay safe. This will be done using functionalized plasmonic nanoparticles (PNPs), which will selectively attach to Gram-negative bacterial cells and crosslink them in clusters but will keep them alive. The second step involves a lethal approach, where those PNP-bound bacterial clusters will be laser irradiated to kill all bacterial cells, just like photothermal therapy kills cancer cells. Host cells will remain unaffected.

PI

Name: Dr. Nagma Parveen
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Faculty Members

Dr. Nagma Parveen

Chemistry

Biological nanoparticles, Virus-membrane interactions, Surface functionalization, Binding kinetics, Fluorescence imaging

Dr. Tarun Gupta

Civil Engineering

Instruments for aerosol measurement, Engineering control of particles, atmospheric pollutants, secondary organic aerosol, health assessment of inhaled particles, engine exhaust emissions, and risk assessment.

Associated Faculty Members

Dr. Anusmita Sahoo

Biological Sciences and Bioengineering

Dr. Appu Kumar Singh

Biological Sciences and Bioengineering

Dr. Ashwani Kumar Thakur

Biological Sciences and Bioengineering

Dr. Dharmaraja Allimuthu

Chemistry

Dr. Jitendra K. Bera

Chemistry

Dr. Manabendra Chandra

Chemistry

Dr. Nisanth N. Nair

Chemistry

Dr. Sandeep Verma

Chemistry

Dr. Saravanan Matheshwaran

Biological Sciences and Bioengineering

Dr. Santosh K. Misra

Biological Sciences and Bioengineering

Clinical advisors

Dr. Jyotsna Agarwal

Professor & Head, Department of Microbiology
Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow

Microbiology, Molecular Biology, Biotechnology, Infectious Diseases

Patents and publications

  • Manorama Dey, Anurag Sharma A.#, Garvita Dhanawat#, Divya Gupta, Krishnan H. Harshan, and Nagma Parveen*, 2024, Synergistic Binding of SARS-CoV-2 to ACE2 and Gangliosides in Native Lipid Membranes, ACS Infectious Diseases, 10, 907-916
  • Geetanjali Negi#, Anurag Sharma#, Monika Chaudhary, Divya Gupta, Krishnan H. Harshan, and Nagma Parveen*, 2023, SARS-CoV-2 Binding to Terminal Sialic Acid of Gangliosides Embedded in Lipid Membranes, ACS Infectious Diseases, 9, 1346–1361
  • "SARS-CoV-2 Evolved Variants Bind to Sialylated Gangliosides and Inhibited by Tetravalent Sialo-Glycocluster“ Author(s): Negi, Geetanjali; Pandey, Vinay Kumar; Potharaju, Poojitha ; Jaiswal, Manoj; HARSHAN, KRISHNAN; Tiwari, Vinod; Parveen, Nagma. Revision in ACS Infectious Diseases, 2025
  • Growth Phase Contribution in Dictating Drug Transport and Subcellular Accumulation inside Escherichia coli. D. Kumar, A. Gayen, Manabendra Chandra*, ACS Infectious Diseases 2024, 10 (9), 3233-3244
  • Membrane Permeability Dominates over Electrostatic Interactions in Dictating Drug Transport in Osmotically Shocked Escherichia coli, D. Kumar, A. Gayen, M. Chandra*, The Journal of Physical Chemistry B 2024, 128(20), 4911–4921
  • Role of AcrAB-TolC and its components in influx–efflux dynamics of QAC drugs in Escherichia coli revealed using SHG spectroscopy D. Singh, D. Kumar, A. Gayen, M. Chandra* The Journal of Physical Chemistry Letters 2024, 15(31), 7832-7839
  • Deciphering the Dilemma of Community Behavior Promotion and Inhibition by Cationic Bactericide-coated Nanoparticles in Gram-Negative Bacteria, Deepak Kumar, Anindita Gayen*, and Manabendra Chandra*, ACS Applied Materials & Interfaces 2025, 17, 15, 22308-22321 (Biological and Medical Applications of Materials and Interfaces)
  • A review on potential approach for in silico toxicity analysis of respirable fraction of ambient particulate matter. AD Gupta, T Gupta Environmental Monitoring and Assessment 195 (10), 1216, 2023.
  • Influence of ambient particulate matter and environmental factors on the seasonal bioaerosol load in the middle Indo-Gangetic Plain. AD Gupta, V Srivastava, N Yadav, SK Misra, T Gupta Atmospheric Environment, 121081, 2025.
  • Growth Phase Contribution in Dictating Drug Transport and Subcellular Accumulation inside Escherichia coli. D. Kumar, A. Gayen, Manabendra Chandra*, ACS Infectious Diseases 2024, 10 (9), 3233-3244
  • Membrane Permeability Dominates over Electrostatic Interactions in Dictating Drug Transport in Osmotically Shocked Escherichia coli, D. Kumar, A. Gayen, M. Chandra*, The Journal of Physical Chemistry B 2024, 128(20), 4911–4921
  • Role of AcrAB-TolC and its components in influx–efflux dynamics of QAC drugs in Escherichia coli revealed using SHG spectroscopy D. Singh, D. Kumar, A. Gayen, M. Chandra* The Journal of Physical Chemistry Letters 2024, 15(31), 7832-7839
  • Deciphering the Dilemma of Community Behavior Promotion and Inhibition by Cationic Bactericide-coated Nanoparticles in Gram-Negative Bacteria, Deepak Kumar, Anindita Gayen*, and Manabendra Chandra*, ACS Applied Materials & Interfaces 2025, 17, 15, 22308-22321 (Biological and Medical Applications of Materials and Interfaces)

Association and Collaboration

The Gangwal School is a unique and socially relevant project with a far-reaching impact on the country's healthcare needs. Besides the R&D and its impact, the state-of-the-art hospital complex being built will also be a boon to needy patients in Kanpur. The Institute seeks funding from alumni, corporates (CSR), and philanthropists to execute the project. The Institute has set a process to accept donations for infrastructure, research, and innovation. Gangawal has an established process for naming functional units (departments, centers, wards, etc.), assets (buildings, rooms, laboratory space, etc.), faculty chairs/fellowships, student awards, and named lecture series to honor the donors. Potential donors are encouraged to get in touch with us for more details.

Please get in touch with the Gangwal School (This email address is being protected from spambots. You need JavaScript enabled to view it. ) or the Dean of Resources and Alumni (This email address is being protected from spambots. You need JavaScript enabled to view it. ) for a follow-up discussion.

To learn about the donation already received, please check here.

The Gangwal School is a unique project which will be developed with support from philanthropists, IITK alumni, and corporates. The fund being raised is mainly for the fixed assets and to bridge the working capital gap in the first 3-4 years. The Institute seeks funding from alumni, corporates (CSR), and philanthropists for this project (details are given here.). The Institute has already secured significant funding through donations, and some donations are for the naming rights for the School, Hospital, Building, and Centers.

Founders Circle

Mr. Muktesh Pant (BT/CHE/1976) click here.
YouTube Video

Dr. Dev Joneja (BT/ME/1984)
YouTube Video

Mr. Hemant Jalan (BT/CHE/1977)
YouTube Video

Mr. Anil Bansal (BT/MSE/1977)
YouTube Video

Mr. Rakesh Gangwal (BT/ME/1975)

Mr. Deepak Narula (BT/EE/1985)
Founder and Managing Partner of Metacapital Management, generously supported Gangwal School project. He is the first to join the league of Co-Founders Circle of the School.

Mr. Narayana Murthy (MT/EE/1969), Founder of Infosys, generously supported Center of Excellence in Cardiovascular and Pulmonary Disease Research.

Ms. Sudha Murty, former Chairperson, Infosys Foundation, generously contributed to our flagship project “Hridyantra.”

Batch of 1976 has generously contributed to our flagship project “Hridyantra.”

YouTube Video

Corporate Donors

JK Cement Limited, a reputed firm in Kanpur, has extended generous support to build a 450 bedded superspeciality hospital on the Gangwal School campus. This hospital will be named after Late Mr. Yadupati Singhania, a distinguished alumnus of the institute (BT/CE/1977) and an illustrious industrialist who played a critical role in setting up the J.K Cement Ltd. For more information, see here. .

YouTube Video

REC Limited generously supported the construction of studio apartments for the resident doctors. see here.

IIT Kanpur and HDFC Bank Limited have inked a pact to work together on establishing an Emergency and Trauma Care Center at Super Specialty Hospital on the campus as part of the Institution’s ambitious initiative to establish Gangwal School of Medical Sciences and Technology.

IBM India Private Limited generously supported the construction of the academic complex of the Gangwal School. This complex will house state-of-the-art research laboratories and academic units.

ICICI Bank generously supported for the setting up of Pathology lab facility at the Health Center, IITK.​

The Indian Institute of Technology Kanpur and the Gangwal School of Medical Sciences and Technology hosted ...

Read more...